Basic Information
VIS ID
TVIS44028436
Fusion event
HTLV-1-DIS3L2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr2
Cytoband
q37.1
Reference genome
NCBI36/hg18
Start
232719043/232146089 (Hg38)
End
232719043/232146089 (Hg38)
Orient
+
Location type
Intronic
Target gene
DIS3L2
miRNAs that regulate target gene
hsa-let-7a-5p ; hsa-mir-218-5p
Nearest miRNA
hsa-mir-10b/Upstream/253791; hsa-mir-149/Downstream/26564;
Nearest TSS
ENST00000437798/Upstream/130237; ENST00000498319/Downstream/17515;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/183963, chr2-CpG: 174/Downstream/204881
Upstream sequence
CCAAAGGATAGGGACAGTACTGATGAGGCAGATCCACTCTAGGAGACAGGGATGGCTTCCTGGCCTTGCTGCTATATTCCATGAAGATGAAATGATCTGG
Downstream sequence
GTATATGCTTTGTGGGCCTAGTTCAACATGGAAGTTATAAAGGGAGCACCTTTAGGATAGAATTATGTTGCCTAAGGAAGGGCCATTTATGGTATTCTTA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate