Basic Information
VIS ID
TVIS44028443
Fusion event
HTLV-1-C4orf45 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr4
Cytoband
q32.1
Reference genome
NCBI36/hg18
Start
160076940/158936338 (Hg38)
End
160076940/158936338 (Hg38)
Orient
+
Location type
Intronic
Target gene
C4orf45
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-mir-12113/Upstream/6399822; hsa-mir-1305/Downstream/192464;
Nearest TSS
ENST00000502981/Upstream/65979; ENST00000503328/Downstream/36793;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/166667, chr4-CpG: 149/Downstream/166297
Upstream sequence
AAATCACTGTTTGTTTGAGTTCCAGGGAGTCAGTCTAGTTGCCTAATATAAACCGCAGAAACAGTCATTCACTTGAGTTTCACATAGAGAAATAATGTGG
Downstream sequence
AAACTTCCCTTTAGGACTTCAACATTTTCCTTGCAGCATCAGAACGTGATGTAACTCTGTGTATTCATGTATTTCAAACTTGTGAAGAGGACCGGTGCCA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate