Basic Information
VIS ID
TVIS44028455
Fusion event
HTLV-1-ZFP62 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr5
Cytoband
q35.3
Reference genome
NCBI36/hg18
Start
180218781/180859175 (Hg38)
End
180218781/180859175 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA5G
Target gene
ZFP62
miRNAs that regulate target gene
hsa-let-7e-5p ; hsa-mir-557 ; hsa-mir-507 ; hsa-mir-6505-5p ; hsa-mir-4325 ; hsa-mir-7703 ; hsa-mir-500a-3p ; hsa-mir-137 ; hsa-mir-4795-3p ; hsa-mir-5087 ; hsa-mir-874-5p ; hsa-mir-3189-5p ; hsa-mir-4790-3p ; hsa-mir-92b-3p ; hsa-mir-92a-3p ; hsa-mir-367-3p ; hsa-mir-363-3p ; hsa-mir-32-5p ; hsa-mir-25-3p ; hsa-mir-126-5p ; hsa-mir-656-3p ; hsa-mir-5583-3p ; hsa-mir-605-5p ; hsa-mir-665 ; hsa-mir-4443 ; hsa-mir-6514-3p ; hsa-mir-516b-5p ; hsa-mir-7977 ; hsa-mir-6722-5p ; hsa-mir-650 ; hsa-mir-3612 ; hsa-mir-6811-3p ; hsa-mir-214-5p ; hsa-mir-518c-5p ; hsa-mir-5690 ; hsa-mir-3664-5p ; hsa-mir-514a-5p ; hsa-mir-4714-5p
Nearest miRNA
hsa-mir-10397/Upstream/843778; hsa-mir-4638/Downstream/184228;
Nearest TSS
ENST00000502646/Upstream/9659; ENST00000514448/Downstream/1488;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/27391, chr5-CpG: 81/Downstream/1728
Upstream sequence
GAGCCACTTTTCAAGAGCCGAGACAACTCGTTAGAGAGGAGCCGTGGCCTGCTCTGGCCGAAAACCCCTTCCTATTAACAGACTGCAACTAGCCCGGAAC
Downstream sequence
GACTTTCAATTTGCAGAGTCCAACCATATTCCACAAGACAATCTACCACCTCAAGGTTCACGCGTGGATTCTACACCTTAAATCCTTGGATACTGTCTTT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate