Basic Information
VIS ID
TVIS44028460
Fusion event
HTLV-1-DYNC2H1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr11
Cytoband
q22.3
Reference genome
NCBI36/hg18
Start
102620788/103244849 (Hg38)
End
102620788/103244849 (Hg38)
Orient
+
Location type
Intronic
Target gene
DYNC2H1
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-124-3p ; hsa-mir-331-3p ; hsa-mir-125b-5p ; hsa-let-7a-5p
Nearest miRNA
hsa-mir-10392/Upstream/1724944; hsa-let-7a-2/Downstream/605057;
Nearest TSS
ENST00000527297/Upstream/39938; ENST00000525306/Downstream/37308;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/152529, chr11-CpG: 43/Downstream/791828
Upstream sequence
tatatatctatagttacagttatatacatataagtactatatctatatatagtcatagttatagacatataagtaactatatagttacttttatatatat
Downstream sequence
gtacacacacacatatatatatacacacacataccacacatacacacacacatacacacGCCTGGGGTGATGTTTAAAACTACTCCTTCCCTATCTAGAA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate