Basic Information
VIS ID
TVIS44028471
Fusion event
HTLV-1-ARHGAP32 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr11
Cytoband
q24.3
Reference genome
NCBI36/hg18
Start
128510963/129135858 (Hg38)
End
128510963/129135858 (Hg38)
Orient
+
Location type
Intronic
Target gene
ARHGAP32
miRNAs that regulate target gene
hsa-mir-132-3p ; hsa-mir-423-5p ; hsa-mir-183-5p ; hsa-mir-93-5p ; hsa-mir-6082 ; hsa-mir-139-5p ; hsa-mir-4799-5p ; hsa-mir-6501-3p ; hsa-mir-6838-5p ; hsa-mir-497-5p ; hsa-mir-424-5p ; hsa-mir-195-5p ; hsa-mir-16-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p ; hsa-mir-2278 ; hsa-mir-3119
Nearest miRNA
hsa-let-7a-2/Upstream/613409; hsa-mir-4697/Downstream/1530877;
Nearest TSS
ENST00000527297/Upstream/69045; ENST00000605151/Downstream/28487;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/244520, chr11-CpG: 194/Downstream/142744
Upstream sequence
tccatctcaaaaaaaaacaaacaaaaaaagaatgttgacccaaacctcacatcatgcacaaaaatcaattttaaatagttcacagacccaaacataaaag
Downstream sequence
gttaacatgttcttctataaagtaccttcatgacattgggataggcgaagatttcttaaaaggacacacacggaaaaaacaattattccgacaccctacc
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate