Basic Information
VIS ID
TVIS44028472
Fusion event
HTLV-1-SERPING1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr11
Cytoband
q12.1
Reference genome
NCBI36/hg18
Start
57129315/57605266 (Hg38)
End
57129315/57605266 (Hg38)
Orient
-
Location type
Intronic
Target gene
SERPING1
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-1273g-3p ; hsa-mir-498 ; hsa-mir-6736-5p ; hsa-mir-4701-3p ; hsa-mir-1262 ; hsa-mir-6720-5p ; hsa-mir-7703 ; hsa-mir-6512-3p ; hsa-mir-661 ; hsa-mir-6776-5p ; hsa-mir-4793-3p ; hsa-mir-766-3p ; hsa-mir-6742-3p ; hsa-mir-6849-3p ; hsa-mir-508-5p ; hsa-mir-629-3p ; hsa-mir-6864-3p ; hsa-mir-3672 ; hsa-mir-519e-5p ; hsa-mir-515-5p ; hsa-mir-873-3p ; hsa-mir-5695 ; hsa-mir-519d-5p ; hsa-mir-6839-3p ; hsa-mir-4507 ; hsa-mir-3940-5p ; hsa-mir-23b-5p ; hsa-mir-23a-5p ; hsa-mir-4284 ; hsa-mir-6774-5p ; hsa-mir-635 ; hsa-mir-4772-3p ; hsa-mir-1304-3p ; hsa-mir-6890-3p ; hsa-mir-3681-3p ; hsa-mir-216a-3p ; hsa-mir-128-3p
Nearest miRNA
hsa-mir-129-2/Upstream/861285; hsa-let-7a-2/Downstream/35932;
Nearest TSS
ENST00000527297/Upstream/3221; ENST00000530113/Downstream/1141;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/37253, chr11-CpG: 19/Downstream/41661
Upstream sequence
CTAGGTTGGTGAAAAATACGTAACAGCATTCAATATTAGGGCTTCTATCCCCATCTAGCTGCACACTGGAGCTGTGCCAAGCAAGGTTCTTGGTCTTATG
Downstream sequence
TTGTACTTAGGCATCAGCAAAGCCTGGGAAAATAtcttttttttttttttgagacagaatctcgctctgtcgcccaggctggaatgcagtggcaccatct
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate