Basic Information
VIS ID
TVIS44028473
Fusion event
HTLV-1-ERMP1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr9
Cytoband
p24.1
Reference genome
NCBI36/hg18
Start
5827280/5837280 (Hg38)
End
5827280/5837280 (Hg38)
Orient
+
Location type
Intronic
Target gene
ERMP1
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-335-5p ; hsa-mir-125a-5p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-218-5p ; hsa-mir-4693-5p ; hsa-mir-223-5p ; hsa-mir-4720-3p ; hsa-mir-4804-3p ; hsa-mir-892a ; hsa-mir-4318 ; hsa-mir-4797-5p ; hsa-mir-429 ; hsa-mir-200c-3p ; hsa-mir-200b-3p
Nearest miRNA
hsa-mir-101-2/Upstream/986905; hsa-let-7a-1/Downstream/170546;
Nearest TSS
ENST00000422679/Upstream/4163; ENST00000490518/Downstream/53522;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/4019, chr9-CpG: 135/Downstream/169684
Upstream sequence
aactatgttgcctaggctggacttgaactcctgacctcaagcaatactgctgccttagcctcccaagtaactggtactataggtgtgccactgcacctgg
Downstream sequence
cCAATTGGTTCTTTAGGGGAAAAAAATCAAATTAGAACCTCATACCATATTACACACACATCCACACACACCCACAATATTCAAGTACAATTCAGAATCA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate