Basic Information
VIS ID
TVIS44028477
Fusion event
HTLV-1-SNRNP200 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr2
Cytoband
q11.2
Reference genome
NCBI36/hg18
Start
96328951/96299486 (Hg38)
End
96328951/96299486 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
SNRNP200
miRNAs that regulate target gene
hsa-mir-877-3p ; hsa-mir-151a-5p ; hsa-mir-425-5p ; hsa-mir-548b-3p ; hsa-mir-193b-3p ; hsa-mir-149-5p ; hsa-mir-30b-5p ; hsa-mir-99a-5p
Nearest miRNA
hsa-mir-1285-2/Upstream/7487032; hsa-mir-10b/Downstream/498792;
Nearest TSS
ENST00000437798/Upstream/9631; ENST00000420176/Downstream/6029;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/32933, chr2-CpG: 45/Downstream/5901
Upstream sequence
GCCTCTTCTCGAACCTCCCCGTATACGTCTTCATCACCTTCCTGTGGAAATGACCCCAACTCAACCATGATCTGGAGCTGATCCTGCATCACCACAGAAC
Downstream sequence
CTCTCCCTCAAGTCACCCTAAATTAGCTCAATGGGTAGAGAAATGGCTTTGGGGTGAAACCGAGAGCCTATTGGAACCAAGGTCAGCCTTATTCCAGTGG
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate