Basic Information
VIS ID
TVIS44028494
Fusion event
HTLV-1-FAM160A1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr4
Cytoband
q31.3
Reference genome
NCBI36/hg18
Start
152706327/151565725 (Hg38)
End
152706327/151565725 (Hg38)
Orient
-
Location type
Intronic
Target gene
FAM160A1
miRNAs that regulate target gene
hsa-mir-4745-3p ; hsa-mir-1538 ; hsa-mir-4747-3p ; hsa-mir-6859-5p ; hsa-mir-3916 ; hsa-mir-3125 ; hsa-mir-6856-5p ; hsa-mir-6758-5p ; hsa-mir-6768-3p
Nearest miRNA
hsa-mir-12113/Upstream/3783057; hsa-mir-1305/Downstream/923602;
Nearest TSS
ENST00000502981/Upstream/32713; ENST00000508664/Downstream/101499;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/156004, chr4-CpG: 21/Downstream/195164
Upstream sequence
ACACCTCCCCCAAGTTGCATCAAGCCGTTTATTTCTCTTGCTGTTAACTCATGGTTTTCCTGTTACTGAGTGTTTTTAAACTCTGCAAACACTGGTATCA
Downstream sequence
TAAtagtttggtgcaaaaataattgcggtttttgcccttgaaagtaatggcaaaaaccgcaattacttttgcaccaacctaaTAGTTTCTTACTTGATTC
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate