Basic Information
VIS ID
TVIS44028517
Fusion event
HTLV-1-PCDH15 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr10
Cytoband
q21.1
Reference genome
NCBI36/hg18
Start
56375841/54946075 (Hg38)
End
56375841/54946075 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA10C
Target gene
PCDH15
Nearest miRNA
hsa-mir-1265/Upstream/338118; hsa-mir-107/Downstream/2358404;
Nearest TSS
ENST00000439456/Upstream/144784; ENST00000453639/Downstream/373539;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/2074409, chr10-CpG: 36/Downstream/682233
Upstream sequence
GAATTGACAGTAGAATGTCAGTTAATTTACCCTGAGAAATATATTAACCATATTTCCTTTGCTTGCTCATTATCTCTTAGTAAAAAATATGTAGGAAACC
Downstream sequence
AATGTCATAATTGGGACTATTTTGGTCAGATTAGAATTACACTAAGATGAATCTGTTGTATAATTTTAATGACCAAAGACTTCATAGATAATGAAAGATG
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate