Basic Information
VIS ID
TVIS44028520
Fusion event
HTLV-1-FAM189A1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr15
Cytoband
q13.1
Reference genome
NCBI36/hg18
Start
27432769/29353273 (Hg38)
End
27432769/29353273 (Hg38)
Orient
-
Location type
Intronic
Target gene
FAM189A1
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-mir-1268a/Upstream/862428; hsa-mir-10393/Downstream/1711759;
Nearest TSS
ENST00000557528/Upstream/83444; ENST00000536835/Downstream/99526;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/83334, chr15-CpG: 238/Downstream/216558
Upstream sequence
tattCTCCCCATTGCACAGAATGGCAATATGTTCTCTCCTAGGTGATTGAAAAGGTTTTTGTCTTTAGTCTCTTATGGACTGGTGCATTTGATGGGGATC
Downstream sequence
CAGAAAAAAAGATGGGACTAAGTGCTGCACGCAAAAGAGAACTGGCCATGAAGAGGACCCACCCGCCAGACAAGAGCCCTGTGTGTCTGCCTGGGAAGGA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate