Basic Information
VIS ID
TVIS44028525
Fusion event
HTLV-1-ABITRAM integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr9
Cytoband
q31.3
Reference genome
NCBI36/hg18
Start
110741792/108939691 (Hg38)
End
110741792/108939691 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA9E
Target gene
ABITRAM
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-4423-3p ; hsa-mir-4528 ; hsa-mir-5582-5p ; hsa-mir-6806-5p ; hsa-mir-3622a-5p ; hsa-mir-4463 ; hsa-mir-5197-3p
Nearest miRNA
hsa-let-7a-1/Upstream/2338669; hsa-mir-12126/Downstream/106538;
Nearest TSS
ENST00000422679/Upstream/5151; ENST00000465091/Downstream/23864;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/5015, chr9-CpG: 110/Downstream/73070
Upstream sequence
AAGAAAGTAAAAGCATAACAGAAGGGTTACTGACACAAAAACAATATGAAGAAGTCATGGTGAAACGCATTAATGCCACAACAGCTACGTCATGAGGATT
Downstream sequence
GACATGGAACAAAAAGCAAAGTGGGATTCTTGTTACCTGGCCTAAACCATCAGGGTACTAAAGGAGAAGAACCAGTATATGTAAAGCATACCTAACAGCC
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate