Basic Information
VIS ID
TVIS44028532
Fusion event
HTLV-1-AUTS2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr7
Cytoband
q11.22
Reference genome
NCBI36/hg18
Start
69846056/70743134 (Hg38)
End
69846056/70743134 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA7J
Target gene
AUTS2
miRNAs that regulate target gene
hsa-mir-21-5p ; hsa-mir-222-3p ; hsa-mir-218-5p
Nearest miRNA
hsa-mir-1183/Upstream/3628737; hsa-mir-10399/Downstream/564538;
Nearest TSS
ENST00000635602/Upstream/13995; ENST00000483297/Downstream/20150;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/47433, chr7-CpG: 92/Downstream/46774
Upstream sequence
ATAGAAGGACATAAAATCTGTGCATTTAGGAGGAAATCTAAACTCATATTATTTCAGCTTTTTAGTCTGTTTAGTAAGGGAGTTTCACCAATTCAGTTAC
Downstream sequence
TACTGATAATAAGCTTCCCCTTGTTTTATTTTTGTTTCTTTAAGAAATCTGggccggacactgtggcacacacctgtaatcccagcactttgggaggctg
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate