Basic Information
VIS ID
TVIS44028542
Fusion event
HTLV-1-ADA2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr22
Cytoband
q11.1
Reference genome
NCBI36/hg18
Start
16081388/17220498 (Hg38)
End
16081388/17220498 (Hg38)
Orient
-
Location type
Intronic
Target gene
ADA2
miRNAs that regulate target gene
hsa-mir-6513-5p ; hsa-mir-887-5p ; hsa-mir-3913-5p ; hsa-mir-3122 ; hsa-mir-450a-1-3p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-6788-5p ; hsa-mir-1273h-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-3656 ; hsa-mir-1251-3p ; hsa-mir-6087 ; hsa-mir-6089 ; hsa-mir-1825 ; hsa-mir-520f-3p ; hsa-mir-302c-3p ; hsa-mir-3622a-5p ; hsa-mir-3190-5p ; hsa-mir-3606-5p ; hsa-mir-3675-3p ; hsa-mir-377-5p ; hsa-mir-3926 ; hsa-mir-4537 ; hsa-mir-455-3p ; hsa-mir-4684-5p ; hsa-mir-4786-5p ; hsa-mir-4793-3p ; hsa-mir-548s ; hsa-mir-6086 ; hsa-mir-6499-3p ; hsa-mir-6516-5p ; hsa-mir-6771-3p ; hsa-mir-6849-3p ; hsa-mir-7703
Nearest miRNA
hsa-let-7a-3/Downstream/543682;
Nearest TSS
ENST00000624155/Upstream/913; ENST00000497534/Downstream/1356;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/48410, chr22-CpG: 230/Downstream/148077
Upstream sequence
caagttgtttcaactctctatacttcagtttcctcatctgaaaatgtggataataaaagcacccaccacagagggtccattgtcagaattaaaggaaaaa
Downstream sequence
cacatgcaaagtacctgccacatagaaagctcttgataaatattagccatgactattCTTAGAAGTAACTATTGGGATGCCTCATCCAAGCCAATTAGAA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate