Basic Information
VIS ID
TVIS44028546
Fusion event
HTLV-1-MGA integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr15
Cytoband
q15.1
Reference genome
NCBI36/hg18
Start
39779284/41699794 (Hg38)
End
39779284/41699794 (Hg38)
Orient
+
Location type
Intronic
Target gene
MGA
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-21-5p
Nearest miRNA
hsa-mir-1233-1/Upstream/8116; hsa-mir-10393/Downstream/166701;
Nearest TSS
ENST00000557528/Upstream/30070; ENST00000566288/Downstream/34760;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/37654, chr15-CpG: 63/Downstream/74496
Upstream sequence
tttcaccgtgttagccaggatggtcttgatctcctgaccttgtgatccgcccgcctcggcctcccaaTTATGTGTTTGTTTTTATAATTTTGGAGGAAGG
Downstream sequence
GTCTTCCTTGTCCTTTAGTAGTATATTTAGGTGTGTAAACAGTAGAATACTTTTCTGTCTCATGTTTTGGCTGCAAACATCTATTTTATATATTTGATGT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate