Basic Information
VIS ID
TVIS44028551
Fusion event
HTLV-1-CDH4 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr20
Cytoband
q13.33
Reference genome
NCBI36/hg18
Start
59772466/61764015 (Hg38)
End
59772466/61764015 (Hg38)
Orient
+
Location type
Intronic
Target gene
CDH4
miRNAs that regulate target gene
hsa-mir-1-3p ; hsa-mir-7111-3p ; hsa-mir-5006-3p ; hsa-mir-4755-5p ; hsa-mir-623 ; hsa-mir-1236-3p ; hsa-mir-6515-3p ; hsa-mir-6832-3p ; hsa-mir-211-5p ; hsa-mir-204-5p ; hsa-mir-570-3p
Nearest miRNA
hsa-mir-103a-2/Upstream/1199390; hsa-mir-1-1/Downstream/189531;
Nearest TSS
ENST00000382410/Upstream/8959; ENST00000635124/Downstream/217417;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/219359, chr20-CpG: 33/Downstream/9027
Nearest cancer related gene
CDH4(TSG, No orient, 0)
Upstream sequence
TTTTTTCTTTTTCAAAAAAACAGAAAAAGACGATCATGTAAAGCCTGCCCCAGGTCAGTTTTGCATTCTTTGTCTCTCGCTTGCGAGTGATGAGGGGAGG
Downstream sequence
GAAATGATCCGAGTTTTGCTGATACTGAGCTGTCCCTGGAGACCTCACCTTGCAGCCACAGCCAGTTACAGCCTCATCACACAGACAGGAGAGCAAGACC
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate