VISDB Viral Integration Site DataBase

VIS ID

TVIS44028556

Fusion event

HTLV-1-CHEK2 integration

Validated

No

Detection method

HTS

Data source

Curated

Sample type

Disease

Not given

Quality evaluation

Normal

Reported year

2019

PubMed ID

Virus name

HTLV-1

Subtype

HTLV-1c

Reference genome

Chromosome

chr22

Cytoband

q12.1

Reference genome

Start

End

27422627/28696639 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-182-5p ; hsa-mir-2053 ; hsa-mir-513a-5p ; hsa-mir-4465 ; hsa-mir-26b-5p ; hsa-mir-26a-5p ; hsa-mir-1297 ; hsa-mir-8068 ; hsa-mir-5697 ; hsa-mir-6074 ; hsa-mir-5694 ; hsa-mir-383-5p ; hsa-mir-376c-3p ; hsa-mir-595 ; hsa-mir-4803 ; hsa-mir-27a-3p ; hsa-mir-3681-3p ; hsa-mir-216a-3p ; hsa-mir-27b-3p ; hsa-mir-128-3p ; hsa-mir-4999-3p ; hsa-mir-7153-3p ; hsa-mir-3680-5p ; hsa-mir-2113 ; hsa-mir-548q ; hsa-mir-548aw ; hsa-mir-1468-3p ; hsa-mir-548x-5p ; hsa-mir-548g-5p ; hsa-mir-548f-5p ; hsa-mir-548aj-5p ; hsa-mir-5695 ; hsa-mir-3691-3p ; hsa-mir-6736-3p ; hsa-mir-454-3p ; hsa-mir-4295 ; hsa-mir-3666 ; hsa-mir-301b-3p ; hsa-mir-301a-3p ; hsa-mir-130b-3p ; hsa-mir-130a-3p ; hsa-mir-519c-3p ; hsa-mir-519b-3p ; hsa-mir-519a-3p ; hsa-mir-559 ; hsa-mir-548y ; hsa-mir-548w ; hsa-mir-548o-5p ; hsa-mir-548j-5p ; hsa-mir-548i ; hsa-mir-548h-5p ; hsa-mir-548d-5p ; hsa-mir-548c-5p ; hsa-mir-548bb-5p ; hsa-mir-548b-5p ; hsa-mir-548ay-5p ; hsa-mir-548au-5p ; hsa-mir-548as-5p ; hsa-mir-548ar-5p ; hsa-mir-548aq-5p ; hsa-mir-548ap-5p ; hsa-mir-548am-5p ; hsa-mir-548ak ; hsa-mir-548ae-5p ; hsa-mir-548ad-5p ; hsa-mir-548ab ; hsa-mir-548a-5p ; hsa-mir-548n ; hsa-mir-19b-3p ; hsa-mir-19a-3p ; hsa-mir-3942-3p ; hsa-mir-4756-3p ; hsa-mir-3919 ; hsa-mir-205-3p ; hsa-mir-5582-5p ; hsa-mir-124-3p ; hsa-mir-548an

Nearest miRNA

hsa-mir-1286/Upstream/236691; hsa-let-7a-3/Downstream/1310410;

Nearest TSS

Nearest CpG islands

None/Target, chr22-CpG: 279/Upstream/16408, chr22-CpG: 53/Downstream/45239

Nearest cancer related gene

CHEK2(TSG, No orient, 0)

Upstream sequence

aatttttgtattttttgccatgttggccaggttggtctcaaactcctgacctcaggtgatctgcccacctcggcctcccaaagtgctgggattacaggtg

Downstream sequence

tgagccaccatacccagccCACTCGTCCATTTAGACCCCTCCTCTCTCTCTAAGCACAAAGGTCACTTGTACACAACAGAGCTCAATAAATGCTCATTCG