Proximate region of VIS (GRCh38)VISEnhancerEnhancer/PromoterPromoterGene16887641139953691605319715441505
Basic Information
VIS ID
TVIS44028563
Fusion event
HTLV-1-MACROD2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr20
Cytoband
p12.1
Reference genome
NCBI36/hg18
Start
15370150/15441505 (Hg38)
End
15370150/15441505 (Hg38)
Orient
-
Location type
Intronic
Target gene
MACROD2
miRNAs that regulate target gene
hsa-mir-1238-3p ; hsa-mir-670-3p ; hsa-mir-4469 ; hsa-mir-486-5p ; hsa-mir-660-3p ; hsa-mir-4667-3p ; hsa-mir-1470 ; hsa-mir-618 ; hsa-mir-502-5p ; hsa-mir-4786-3p ; hsa-mir-1915-5p ; hsa-mir-6841-3p ; hsa-mir-153-5p ; hsa-mir-6808-3p ; hsa-mir-7973 ; hsa-mir-486-3p ; hsa-mir-4252 ; hsa-mir-4725-5p ; hsa-mir-6852-5p ; hsa-mir-6791-5p ; hsa-mir-4292 ; hsa-mir-504-5p
Nearest miRNA
hsa-mir-103a-2/Upstream/4791810; hsa-mir-1-1/Downstream/3029110;
Nearest TSS
ENST00000382410/Upstream/244647; ENST00000486914/Downstream/111380;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/1445083, chr20-CpG: 50/Downstream/1131686
Upstream sequence
CTAGGGGACCTGACAAAAGAGATGAAAATCCTGGAAACTTAGTTTTTCTGGAATGCAGAGGCAGTGAGAAACCAGTGTCAGTCTTCCTGATGTTCTGTTC
Downstream sequence
CAGATGAACAATTTTGGGACTTAATTAAAAGATTAAGTGTTTcactatgcaatatatgcatggaagaaacttgtatgtgggccctctaattatataaaaa
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate