Basic Information
VIS ID
TVIS44028581
Fusion event
HTLV-1-CLCN5 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chrX
Cytoband
p11.23
Reference genome
NCBI36/hg18
Start
49677447/50026098 (Hg38)
End
49677447/50026098 (Hg38)
Orient
+
Location type
Intronic
Target gene
CLCN5
miRNAs that regulate target gene
hsa-mir-21-5p ; hsa-mir-4535 ; hsa-mir-4776-5p ; hsa-mir-1273e ; hsa-mir-4763-3p ; hsa-mir-1207-5p ; hsa-mir-650 ; hsa-mir-3612 ; hsa-mir-711 ; hsa-mir-6722-3p ; hsa-mir-1909-3p ; hsa-mir-4722-5p ; hsa-mir-1827 ; hsa-mir-219b-3p ; hsa-mir-4649-3p ; hsa-mir-1247-3p ; hsa-mir-6783-5p ; hsa-mir-6893-5p ; hsa-mir-940 ; hsa-mir-6808-5p ; hsa-mir-302f
Nearest miRNA
hsa-mir-1587/Upstream/11415; hsa-let-7f-2/Downstream/2310459;
Nearest TSS
ENST00000429181/Upstream/102694; ENST00000376108/Downstream/16240;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/102714, chrX-CpG: 16/Downstream/255238
Upstream sequence
tattaatatatgcattcaatactataaatatccctctaagcactggtttcactgcatcccacaaattttgataagtggtttcttcattttcatttagttc
Downstream sequence
aaaatgttttttaatttttctttagacttctttaacccatgtgatatttagaagagtgtttaatctccaagtatttgagttttcaagctttgtcttactg
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate