Basic Information
VIS ID
TVIS44028585
Fusion event
HTLV-1-MBTPS1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr16
Cytoband
q24.1
Reference genome
NCBI36/hg18
Start
82699779/84108673 (Hg38)
End
82699779/84108673 (Hg38)
Orient
+
Location type
Intronic
Target gene
MBTPS1
miRNAs that regulate target gene
hsa-mir-769-3p ; hsa-mir-193b-3p ; hsa-let-7c-5p
Nearest miRNA
hsa-mir-1225/Upstream/600265; hsa-mir-11401/Downstream/1099123;
Nearest TSS
ENST00000527434/Upstream/15387; ENST00000565382/Downstream/8122;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/56163, chr16-CpG: 137/Downstream/7634
Upstream sequence
AGCACTTTCTAAAGAGTGCTAACTCTGCCTTTTCTTCTTCCCTTCCTGAAGAATTCTGCTGAAGACAAGAAGGCAGGCGTTCATGGGAGAATGGCAGAAG
Downstream sequence
CCCACTACAGGGTCTTAAGAGTCTGAGCGGAGTGAGGAAGGTATGTGAAGGGAGAGGCACCAGGTGAGGGGGTCAGAGCCTGGCAAGTGAAGAAGGCACC
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
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