Basic Information
VIS ID
TVIS44028597
Fusion event
HTLV-1-CDH18 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr5
Cytoband
p14.3
Reference genome
NCBI36/hg18
Start
20198049/20162183 (Hg38)
End
20198049/20162183 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA5E
Target gene
CDH18
miRNAs that regulate target gene
hsa-let-7e-5p
Nearest miRNA
hsa-mir-10397/Upstream/3006191; hsa-mir-103a-1/Downstream/11773919;
Nearest TSS
ENST00000502646/Upstream/173953; ENST00000513573/Downstream/143382;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/2506569, chr5-CpG: 45/Downstream/143270
Upstream sequence
AGTTCCACTATAAGATTTCACACTCTGAGACAGTCCCAGAAATACATAAAAAACAAAGCTCAATTTCTTTAGGCTTTGTTTTGTAATGTCCTCAGGGCAA
Downstream sequence
AAATCTAGTTCCAATGAAATGTCATTTATCACTCTGCTTACTTGTTTTAAATTAGTTTTTGGTCTCATGATTCCTTGTTTTCTTGCCAGGTCACTAAAGC
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
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