Basic Information
VIS ID
TVIS44028600
Fusion event
HTLV-1-PRR5L integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr11
Cytoband
p13
Reference genome
NCBI36/hg18
Start
36378057/36399931 (Hg38)
End
36378057/36399931 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA11E
Target gene
PRR5L
miRNAs that regulate target gene
hsa-mir-26b-5p ; hsa-mir-502-5p ; hsa-mir-27b-5p ; hsa-mir-6859-5p ; hsa-mir-3916 ; hsa-mir-3125
Nearest miRNA
hsa-mir-1343/Upstream/389727; hsa-let-7a-2/Downstream/7159725;
Nearest TSS
ENST00000527297/Upstream/1519; ENST00000527487/Downstream/1134;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/22083, chr11-CpG: 82/Downstream/109686
Upstream sequence
AGAAAGAAATTCATCTGaatggaaatagccagtccttgaggcccatggctccgccattctgccagccatgtcacatgatctcatttcatctctccagtcc
Downstream sequence
tggaaagtgggcattagtaacagctgaggacttcagactcagtgtgttcaaagtcacacaacttgggagtggccaagttaagactcaaacctgaagccac
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate