Basic Information
VIS ID
TVIS44028608
Fusion event
HTLV-1-ITSN1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr21
Cytoband
q22.11
Reference genome
NCBI36/hg18
Start
33938810/33644634 (Hg38)
End
33938810/33644634 (Hg38)
Orient
+
Location type
Intronic
Target gene
ITSN1
miRNAs that regulate target gene
hsa-mir-296-3p ; hsa-mir-194-5p
Nearest miRNA
hsa-let-7c/Upstream/93906; hsa-mir-3197/Downstream/2076081;
Nearest TSS
ENST00000624081/Upstream/708; ENST00000456489/Downstream/74163;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/1256, chr21-CpG: 36/Downstream/270865
Upstream sequence
TGAACAAATTTTTAATGTACTTTGGAACCCTGCGGATTGCACAGATACTAAGCATTGTGAAATAGGGCATAAAATGAGTGGTAGCAAGTTAGTTCTGTGA
Downstream sequence
AATGTTTGTCGCTGTTAGCATTTTTTTTTTTTTTTGGCAGTCGACTAGCAATTTTCTTTTCCCTAAAGCTTATCTTCAATATTGGTAGTAGAACCTCTGC
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
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