Basic Information
VIS ID
TVIS44028640
Fusion event
HTLV-1-ZNF83 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr19
Cytoband
q13.41
Reference genome
NCBI36/hg18
Start
57822677/52627612 (Hg38)
End
57822677/52627612 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA19A
Target gene
ZNF83
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-340-5p ; hsa-mir-155-5p ; hsa-mir-629-3p ; hsa-mir-519e-5p ; hsa-mir-515-5p ; hsa-mir-329-5p ; hsa-mir-4262 ; hsa-mir-181d-5p ; hsa-mir-181c-5p ; hsa-mir-181b-5p ; hsa-mir-181a-5p ; hsa-mir-219a-2-3p ; hsa-mir-219b-3p ; hsa-mir-4452 ; hsa-mir-6844 ; hsa-mir-3925-3p ; hsa-mir-766-3p ; hsa-mir-510-3p ; hsa-mir-488-3p ; hsa-mir-1257 ; hsa-mir-6730-5p ; hsa-mir-5681a ; hsa-mir-4302 ; hsa-mir-4715-3p ; hsa-mir-3064-3p ; hsa-mir-770-5p ; hsa-mir-4712-5p ; hsa-mir-6809-3p ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-6873-3p ; hsa-mir-6845-3p ; hsa-mir-4752 ; hsa-mir-3911 ; hsa-mir-8056 ; hsa-mir-3691-5p ; hsa-mir-376c-5p ; hsa-mir-376b-5p ; hsa-mir-4320 ; hsa-mir-1825 ; hsa-mir-664a-3p ; hsa-mir-4729 ; hsa-mir-29b-2-5p ; hsa-mir-584-5p ; hsa-mir-3193 ; hsa-mir-1539 ; hsa-mir-758-5p ; hsa-mir-218-2-3p ; hsa-mir-8076
Nearest miRNA
hsa-let-7e/Upstream/345719; hsa-mir-10394/Downstream/1039067;
Nearest TSS
ENST00000633603/Upstream/9572; ENST00000594546/Downstream/9474;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/25716, chr19-CpG: 46/Downstream/10310
Upstream sequence
ttagccaggcatgatggcaggcacctgtaatcccagctactgaggcaggagaatcccttgaacctgggaggcagaaattgcaatgagctgagatcatacc
Downstream sequence
agtactctggcctgagcaaaagagcaaaactcagtctcaactaaataaataaataaatattgggtactgggcttaatgtcaaggtgatgaactactctgt
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate