Basic Information
VIS ID
TVIS44028663
Fusion event
HTLV-1-ZMAT4 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr8
Cytoband
p11.21
Reference genome
NCBI36/hg18
Start
40539661/40562985 (Hg38)
End
40539661/40562985 (Hg38)
Orient
+
Location type
Intronic
Target gene
ZMAT4
miRNAs that regulate target gene
hsa-mir-26b-5p ; hsa-mir-7977 ; hsa-mir-6131 ; hsa-mir-1207-3p ; hsa-mir-6768-5p ; hsa-mir-2909 ; hsa-mir-1296-5p ; hsa-mir-383-3p ; hsa-mir-4761-3p ; hsa-mir-7843-5p ; hsa-mir-6879-5p ; hsa-mir-6735-5p ; hsa-mir-4632-5p ; hsa-mir-8485 ; hsa-mir-4436b-3p ; hsa-mir-3941 ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-335-3p ; hsa-mir-133b ; hsa-mir-133a-3p ; hsa-mir-6848-3p ; hsa-mir-6843-3p ; hsa-mir-7107-3p ; hsa-mir-6753-3p ; hsa-mir-6503-5p ; hsa-mir-4527 ; hsa-mir-9-5p ; hsa-mir-302a-5p ; hsa-mir-3121-5p ; hsa-mir-4793-5p ; hsa-mir-5196-3p ; hsa-mir-200b-5p ; hsa-mir-200a-5p ; hsa-mir-501-5p ; hsa-mir-513c-3p ; hsa-mir-513a-3p ; hsa-mir-3606-3p
Nearest miRNA
hsa-mir-124-1/Upstream/10605637; hsa-mir-10400/Downstream/708063;
Nearest TSS
ENST00000518652/Upstream/42827; ENST00000521725/Downstream/134352;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/1039971, chr8-CpG: 20/Downstream/334660
Upstream sequence
aaaagtgttgacttctcttcctttgtcacgacgtgtgtgtgcacacatgtgtgcagtgtaaacatatgtgtgtttattcctcaagttcctcttactgtac
Downstream sequence
acactcaccttgagtgaactcatctactcccatatcagacacttcaaccagctcctgtgaccctaagcatcctgaatctgaatcttcagccctcatttgt
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate