Basic Information
VIS ID
TVIS44028676
Fusion event
HTLV-1-SMG5 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr1
Cytoband
q22
Reference genome
NCBI36/hg18
Start
154508358/156271943 (Hg38)
End
154508358/156271943 (Hg38)
Orient
+
Location type
Intronic
Target gene
SMG5
miRNAs that regulate target gene
hsa-mir-708-5p ; hsa-mir-130b-5p ; hsa-mir-106b-3p ; hsa-mir-193b-3p ; hsa-mir-331-3p
Nearest miRNA
hsa-mir-101-1/Upstream/320607; hsa-mir-1182/Downstream/148398;
Nearest TSS
ENST00000473358/Upstream/4355; ENST00000456810/Downstream/10882;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/25835, chr1-CpG: 35/Downstream/10505
Upstream sequence
tggcctcccaaagtgctaggattacaggtatgagctaccaggccctgccAAAAATGTTGTTTTTTATTCTAACAGCTAAGAGTCAGACCCAGGGAAGCAG
Downstream sequence
TGACCCACCCTGCTGGTCCTTCCACGTATATTACCACATTAACACACTCCAGAATTCTCATGCTCTTGCCAGAAGCCACCTTAGTAACATTTTACCAACT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate