Basic Information
VIS ID
TVIS44028682
Fusion event
HTLV-1-CACNA1D integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr3
Cytoband
p21.1
Reference genome
NCBI36/hg18
Start
53762193/53753126 (Hg38)
End
53762193/53753126 (Hg38)
Orient
+
Location type
Intronic
Target gene
CACNA1D
miRNAs that regulate target gene
hsa-mir-136-5p
Nearest miRNA
hsa-let-7g/Upstream/906574; hsa-mir-12124/Downstream/2099366;
Nearest TSS
ENST00000440867/Upstream/3752; ENST00000637081/Downstream/496;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/257047, chr3-CpG: 61/Downstream/70239
Upstream sequence
AGCACATCAAACCAGCTCTCAGTGCTGTCTGGACAGTAGGTCTAAAGATAGGGATAAATTTTCTGGCATTTTTCTTAACCTAAGAGTTCTTTTTGAATGA
Downstream sequence
AAAGGACTGTGTGCTGACGTAGAAGAAAGTGTAAAATCAAGAAAACACTGCCTTTTATTCAACATAAACTTACATGGCATAAAATTTATCCCTAACCAAA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
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