Basic Information
VIS ID
TVIS44028691
Fusion event
HTLV-1-DHDDS integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr1
Cytoband
p36.11
Reference genome
NCBI36/hg18
Start
26670201/26471123 (Hg38)
End
26670201/26471123 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1A
Target gene
DHDDS
miRNAs that regulate target gene
hsa-mir-6513-5p ; hsa-mir-887-5p ; hsa-mir-3913-5p ; hsa-mir-3122 ; hsa-mir-450a-1-3p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-6788-5p ; hsa-mir-1273h-5p ; hsa-mir-30c-2-3p ; hsa-mir-4316 ; hsa-mir-30c-1-3p ; hsa-mir-4710 ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-6804-5p ; hsa-mir-6089 ; hsa-mir-5008-5p
Nearest miRNA
hsa-mir-12136/Upstream/564669; hsa-mir-101-1/Downstream/83419;
Nearest TSS
ENST00000473358/Upstream/3841; ENST00000468388/Downstream/1327;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/38758, chr1-CpG: 159/Downstream/752
Upstream sequence
TGGAGTAGGGAGAAGCTGCCCCAGGAGGCGATGTAGTGGTGGAAAGAAGAGGCAGAGAGGTCGTCGTCGTCGCCCAGCAGCAAGGGCTGCAAAATAGTAG
Downstream sequence
AACTCGTGGTTGCTTTGGACAGGTGTGATTTGTGCAAGCCAGGTTCAACCCTTGCCTCAAGAAATCAGATGGGACCAATTTAGTGTCCTTCCACCTGTGA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate