Basic Information
VIS ID
TVIS44028693
Fusion event
HTLV-1-ATG7 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr3
Cytoband
p25.3
Reference genome
NCBI36/hg18
Start
11305690/11289004 (Hg38)
End
11305690/11289004 (Hg38)
Orient
-
Location type
Intronic
Target gene
ATG7
miRNAs that regulate target gene
hsa-mir-375 ; hsa-mir-320c ; hsa-mir-96-5p ; hsa-mir-4687-5p ; hsa-mir-4726-5p ; hsa-mir-6749-3p ; hsa-mir-4640-5p ; hsa-mir-6837-5p ; hsa-mir-4685-5p ; hsa-mir-3918 ; hsa-mir-4733-3p ; hsa-mir-6895-5p ; hsa-mir-6753-5p ; hsa-mir-4708-3p ; hsa-mir-6826-5p ; hsa-mir-3922-5p ; hsa-mir-451b ; hsa-mir-4753-5p ; hsa-mir-154-5p ; hsa-mir-3127-5p ; hsa-mir-6802-3p ; hsa-mir-6879-3p ; hsa-mir-4518 ; hsa-mir-1266-5p ; hsa-mir-6783-5p ; hsa-mir-4640-3p ; hsa-mir-34a-5p ; hsa-mir-210-3p ; hsa-mir-106a-5p
Nearest miRNA
hsa-mir-12127/Upstream/894442; hsa-let-7g/Downstream/4207235;
Nearest TSS
ENST00000440867/Upstream/11785; ENST00000464282/Downstream/19438;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/16553, chr3-CpG: 38/Downstream/199306
Upstream sequence
ACTGAACTTCTTGGCTACTGCAGGCTTTCTTACACCACTAGAGTTCTTGCTCATTACAGTGTTGAATCCCTATCAAAACCTTTCCTGTTTAATTGGCAGT
Downstream sequence
GACACAATCCCATCTTGTGTAACTCAGGATGTTTCACATCCTGAAATAGTTTGAAATAAAATTGAAACACACTTACATTGATGCCTATGTTAATTTCTTT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate