Basic Information
VIS ID
TVIS44028699
Fusion event
HTLV-1-ANO6 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr12
Cytoband
q12
Reference genome
NCBI36/hg18
Start
43899258/45219208 (Hg38)
End
43899258/45219208 (Hg38)
Orient
+
Location type
Intronic
Target gene
ANO6
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-192-5p ; hsa-mir-615-3p ; hsa-mir-182-5p ; hsa-mir-10a-5p ; hsa-let-7a-5p ; hsa-mir-3620-3p ; hsa-mir-218-5p ; hsa-mir-631 ; hsa-mir-3661 ; hsa-mir-500b-3p ; hsa-mir-3908
Nearest miRNA
hsa-mir-1244-3/Upstream/2895349; hsa-let-7i/Downstream/1968604;
Nearest TSS
ENST00000382841/Upstream/3088; ENST00000551667/Downstream/73475;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/2239, chr12-CpG: 72/Downstream/507735
Upstream sequence
AATTATTTTGACACGAGTTCCTGGGTATACCATTGGGCGTTATAATGGCCTAATTTGCAAGAGACCTCCCCCTCCCCCCAAAAAAAAACTTTCTAACTGG
Downstream sequence
ATGGGGTCCCTGATTATATCATAGAGATGCTTTATGTATGTATATGGAAATGTGCCCTCTAGTAGCTGGAATTTAGAGCCTTTTAAACAGTGGGTTCCTG
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate