Basic Information
VIS ID
TVIS44028704
Fusion event
HTLV-1-LPCAT2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr16
Cytoband
q12.2
Reference genome
NCBI36/hg18
Start
54122492/55531079 (Hg38)
End
54122492/55531079 (Hg38)
Orient
+
Location type
Intronic
Target gene
LPCAT2
miRNAs that regulate target gene
hsa-mir-1827 ; hsa-mir-2682-5p ; hsa-mir-34b-5p ; hsa-mir-449c-5p
Nearest miRNA
hsa-mir-1225/Upstream/4788702; hsa-mir-11401/Downstream/714441;
Nearest TSS
ENST00000527434/Upstream/2586; ENST00000576365/Downstream/960;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/21717, chr16-CpG: 126/Downstream/124607
Upstream sequence
agattttacgattcACTGTATACCCATTAATCGTTAGTAGTTTAGTTGTTGAATTTTCACTGAATAAAATATATTTGATATTGTATCCCGTTGTCATAGG
Downstream sequence
AAACCCACTTTTAAACTGGAGAATGGAATTATATCCTTTCataatttttattttataaataaCCTGTTATTGTGGCAATGTAGCCCAATAATATTTTCCC
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate