Basic Information
VIS ID
TVIS44028706
Fusion event
HTLV-1-MYO1B integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr2
Cytoband
q32.3
Reference genome
NCBI36/hg18
Start
191873096/191300125 (Hg38)
End
191873096/191300125 (Hg38)
Orient
+
Location type
Intronic
Target gene
MYO1B
miRNAs that regulate target gene
hsa-mir-1-3p ; hsa-mir-378a-5p ; hsa-mir-363-3p ; hsa-mir-4703-3p ; hsa-mir-145-3p ; hsa-mir-6780b-3p ; hsa-mir-4698 ; hsa-mir-7852-3p ; hsa-mir-513c-3p ; hsa-mir-513a-3p ; hsa-mir-3606-3p ; hsa-mir-3646 ; hsa-mir-561-3p ; hsa-mir-3662
Nearest miRNA
hsa-mir-10b/Upstream/2167014; hsa-mir-1244-1/Downstream/15483109;
Nearest TSS
ENST00000437798/Upstream/23240; ENST00000496992/Downstream/69439;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/53911, chr2-CpG: 88/Downstream/377722
Upstream sequence
TGGTGGGTCATTTTCCACTTCCTTTAGTGTATTTTCCTGCATTTTTCTTTGCAGATGTTCATCTTTGATGGTATTTTGAAACAGGGTCAATGCTAACTTG
Downstream sequence
GTTCCCTACTAAAACAGCCTGGCATTCTCAAACAGGATGTTTGTGATGTAAGGGGGTAAGATGACCTTAGCTTTTGATGCATTCTAACTGTAAATATTTC
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate