Basic Information
VIS ID
TVIS44028710
Fusion event
HTLV-1-RPTOR integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr17
Cytoband
q25.3
Reference genome
NCBI36/hg18
Start
76374208/80785813 (Hg38)
End
76374208/80785813 (Hg38)
Orient
+
Location type
Intronic
Target gene
RPTOR
miRNAs that regulate target gene
hsa-mir-27b-3p ; hsa-mir-27a-3p ; hsa-mir-155-5p
Nearest miRNA
hsa-mir-10226/Upstream/366320; hsa-mir-1250/Downstream/339463;
Nearest TSS
ENST00000595228/Upstream/42526; ENST00000576366/Downstream/19819;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/39386, chr17-CpG: 24/Downstream/15978
Upstream sequence
gacaagaatgacccagtttgtatgatcagctctcacaGTGACAATGACAGTCATGATGGGGATGTGTTTTGAGGGCCTTTTCCTCTCCTTTGCCGAGGAA
Downstream sequence
CTGCACAGGGAATGCTGATGGCGAGACCTCCAGGGAAGCCACTTATGTCTTCACCACTAGAGAAGGGGGGACTCTGCATGTTGGCGAGAGCAGGGGGGTG
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
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