Basic Information
VIS ID
TVIS44028711
Fusion event
HTLV-1-MRPL58 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr17
Cytoband
q25.1
Reference genome
NCBI36/hg18
Start
70522417/75014727 (Hg38)
End
70522417/75014727 (Hg38)
Orient
+
Location type
Intronic
Target gene
MRPL58
miRNAs that regulate target gene
hsa-mir-33a-5p ; hsa-mir-26b-5p ; hsa-mir-126-5p ; hsa-mir-4464 ; hsa-mir-4477a ; hsa-mir-4748 ; hsa-mir-514b-3p ; hsa-mir-514a-3p ; hsa-mir-655-3p ; hsa-mir-374c-5p ; hsa-mir-6134 ; hsa-mir-7854-3p ; hsa-mir-549a
Nearest miRNA
hsa-mir-10226/Upstream/266028; hsa-mir-1250/Downstream/391342;
Nearest TSS
ENST00000595228/Upstream/1990; ENST00000583772/Downstream/5502;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/1652, chr17-CpG: 38/Downstream/19854
Upstream sequence
tagagacagggttttcaccatgttggccaggctagtctcaaactcctgacctcaaatgatctgctcgcctcagcctcccaaagtgctgggattacaggcg
Downstream sequence
tgagccaccatgcccagccaagtctggggccttgagcagtgaaaggattgagttgctattaactgagatgagagagtggcaatagcaTTCATTTGttcat
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate