Basic Information
VIS ID
TVIS44028720
Fusion event
HTLV-1-C5orf66 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr5
Cytoband
q31.1
Reference genome
NCBI36/hg18
Start
134584695/135221106 (Hg38)
End
134584695/135221106 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA5C
Target gene
C5orf66
Nearest miRNA
hsa-mir-10397/Upstream/995254; hsa-mir-103a-1/Downstream/581879;
Nearest TSS
ENST00000502646/Upstream/89857; ENST00000554670/Downstream/26709;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/29377, chr5-CpG: 31/Downstream/105925
Upstream sequence
CTAGGAAGGGTTGAAGGATCATCTGATTGCTGTGATATTTGGCAGGTATGTTTCAGTACATTCATGGGGGCTTCCAGAGGATCCCAGAGGCCTCGTGGTC
Downstream sequence
AAGGGCCATGGACTCTGTTTTCTCATGGTCAATGGGCTGAGGTTAGCAAGGAGAGAGGTACAGGAGAGGGCAGAGTGGTACATCCAACAACTGGTAGTTG
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
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