Basic Information
VIS ID
TVIS44028728
Fusion event
HTLV-1-ITSN2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr2
Cytoband
p23.3
Reference genome
NCBI36/hg18
Start
24417047/24340674 (Hg38)
End
24417047/24340674 (Hg38)
Orient
+
Location type
Intronic
Target gene
ITSN2
miRNAs that regulate target gene
hsa-mir-148b-3p ; hsa-mir-124-3p ; hsa-mir-21-5p ; hsa-mir-320c ; hsa-mir-186-5p ; hsa-mir-149-5p ; hsa-mir-3692-3p ; hsa-mir-513a-5p ; hsa-mir-16-1-3p ; hsa-mir-126-5p ; hsa-mir-551b-5p ; hsa-mir-216a-3p ; hsa-mir-128-3p ; hsa-mir-27a-3p ; hsa-mir-3681-3p ; hsa-mir-27b-3p ; hsa-mir-144-3p
Nearest miRNA
hsa-mir-3125/Upstream/4992169; hsa-mir-10b/Downstream/987966;
Nearest TSS
ENST00000437798/Upstream/12556; ENST00000469850/Downstream/19635;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/164874, chr2-CpG: 120/Downstream/19077
Upstream sequence
tccagcctctgtcccaccagggaaacatgatcccaacttctaataccatagattcgttctgtctgctaaggtacttcatatgaatggaattatgtagccc
Downstream sequence
gttgtgtctcttttgttcagcatttggtctataagTTGTGTCATTATAGATCCTGTGTTCTCAAAAAAGGAAAAAAAACACACACACACACACACATATA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate