Basic Information
VIS ID
TVIS44028732
Fusion event
HTLV-1-NUP210 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr3
Cytoband
p25.1
Reference genome
NCBI36/hg18
Start
13412883/13396383 (Hg38)
End
13412883/13396383 (Hg38)
Orient
-
Location type
Intronic
Target gene
NUP210
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-1-3p ; hsa-mir-1229-3p ; hsa-mir-296-3p ; hsa-mir-18a-3p ; hsa-mir-423-3p ; hsa-mir-15b-5p ; hsa-mir-221-3p ; hsa-mir-92a-3p ; hsa-mir-2113 ; hsa-mir-218-5p ; hsa-mir-6844 ; hsa-mir-514b-5p ; hsa-mir-513c-5p ; hsa-mir-561-5p ; hsa-mir-6882-3p ; hsa-mir-8077 ; hsa-mir-7160-5p ; hsa-mir-4663 ; hsa-mir-1286 ; hsa-mir-1827 ; hsa-mir-3117-5p ; hsa-mir-6817-5p ; hsa-mir-4769-3p ; hsa-mir-4649-3p ; hsa-mir-1976 ; hsa-mir-6893-3p ; hsa-mir-370-3p ; hsa-mir-5000-3p ; hsa-mir-4436a ; hsa-mir-6830-5p ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-1197 ; hsa-mir-6757-3p ; hsa-mir-8080 ; hsa-mir-193a-5p
Nearest miRNA
hsa-mir-12127/Upstream/3001821; hsa-let-7g/Downstream/2099856;
Nearest TSS
ENST00000440867/Upstream/41689; ENST00000418189/Downstream/23926;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/112954, chr3-CpG: 140/Downstream/23087
Upstream sequence
ctaagaaatcctgATCCAGAAATTTTTTTTCAAAAACAGGAGCTAGAGTTGTCAGAAAAGGTTTCAAAGACAAAGTGAGCCTTGGTTTGGACTTGGTTTG
Downstream sequence
GGGGCAGATCATCTGAAAGGCATCTTTTGCCTGACTTTTATTTTCTCTGACAAGAATTTTAACCTACAAAGTTTCCCTTACTggccaggtgcggtggctc
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate