Basic Information
VIS ID
TVIS44028739
Fusion event
HTLV-1-PRDM5 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr4
Cytoband
q27
Reference genome
NCBI36/hg18
Start
121982674/120842069 (Hg38)
End
121982674/120842069 (Hg38)
Orient
+
Location type
Intronic
Target gene
PRDM5
miRNAs that regulate target gene
hsa-mir-8063
Nearest miRNA
hsa-mir-12113/Upstream/6185215; hsa-mir-1305/Downstream/4665190;
Nearest TSS
ENST00000502981/Upstream/20721; ENST00000507782/Downstream/80612;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/775068, chr4-CpG: 127/Downstream/79924
Nearest cancer related gene
PRDM5(TSG, No orient, 0)
Upstream sequence
TTACGTATGATTTGAAAGCACACTACCACTTCATAGTAAATACTTCTTTTCTCAGTAGCCTTAGCTATTTCATTATTCTATATCCTAGTTTTCTGAGTGA
Downstream sequence
GTCCAGACTGAACTCTCTGGTTGTTAATCAACAGAGTATCTGAATTAAAGGTTCTGCTTGTCTGTGGTTATATCTGTAAAAAGACTTTTGACATTAACGA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
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