Basic Information
VIS ID
TVIS44028747
Fusion event
HTLV-1-ADAMTS20 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr12
Cytoband
q12
Reference genome
NCBI36/hg18
Start
42199327/43519257 (Hg38)
End
42199327/43519257 (Hg38)
Orient
+
Location type
Intronic
Target gene
ADAMTS20
miRNAs that regulate target gene
hsa-mir-6739-3p ; hsa-mir-4677-5p ; hsa-mir-7156-5p ; hsa-mir-4273 ; hsa-mir-22-5p ; hsa-mir-2116-5p
Nearest miRNA
hsa-mir-1244-3/Upstream/1195398; hsa-let-7i/Downstream/3668555;
Nearest TSS
ENST00000382841/Upstream/79545; ENST00000546780/Downstream/32664;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/928679, chr12-CpG: 126/Downstream/31659
Upstream sequence
tgacttaaaatgtcctaaatgTAGAGGTGGATTCACCATGAACCTAAAAAAAGCTTAAACTTTTGGTCTCTAAAaattatgtattcataattttctatta
Downstream sequence
aagagcactgcaactgtttaatcttcaggattccacaacctggagccacccATAACTACATGATCTGGCCTCCCACTACCATTATTTCTACTAATTTCTT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate