Basic Information
VIS ID
TVIS44028748
Fusion event
HTLV-1-FMN2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr1
Cytoband
q43
Reference genome
NCBI36/hg18
Start
238509673/240279750 (Hg38)
End
238509673/240279750 (Hg38)
Orient
+
Location type
Intronic
Target gene
FMN2
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-4738-3p ; hsa-mir-374c-3p ; hsa-mir-4282
Nearest miRNA
hsa-mir-101-1/Upstream/2808559; hsa-mir-3123/Downstream/852522;
Nearest TSS
ENST00000473358/Upstream/34490; ENST00000543681/Downstream/49394;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/71524, chr1-CpG: 26/Downstream/126270
Upstream sequence
ACTTAGAAGCAACTTTTTATTAATTAAAAGCACATCAGATAAATCCTAATATTTGAAACACCTCCCCATATTTAACTAATTCCTCATTCTTCTAGACAAG
Downstream sequence
GAAACATTAAAGTAATTTTTACACATCAACATATACTTCAGAAGAGAAAAAAGAAACCTTCATTAACTGAACAAATAACAAAATATGACTCAACATACAC
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate