Basic Information
VIS ID
TVIS44028758
Fusion event
HTLV-1-ANKRD62 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr18
Cytoband
p11.21
Reference genome
NCBI36/hg18
Start
12151528/12161529 (Hg38)
End
12151528/12161529 (Hg38)
Orient
+
Location type
Intronic
Target gene
ANKRD62
miRNAs that regulate target gene
hsa-mir-619-5p ; hsa-mir-5089-5p ; hsa-mir-6807-5p ; hsa-mir-556-3p ; hsa-mir-7151-3p ; hsa-mir-5095 ; hsa-mir-550a-5p ; hsa-mir-550a-3-5p ; hsa-mir-1271-3p ; hsa-mir-874-5p ; hsa-mir-661 ; hsa-mir-3116 ; hsa-mir-1254 ; hsa-mir-6504-3p ; hsa-mir-4438 ; hsa-mir-640 ; hsa-mir-3934-5p ; hsa-mir-764 ; hsa-mir-125a-3p ; hsa-mir-3157-5p ; hsa-mir-4735-5p ; hsa-mir-6872-3p ; hsa-mir-767-5p ; hsa-mir-378a-5p ; hsa-mir-6821-3p ; hsa-mir-6790-3p ; hsa-mir-3653-5p ; hsa-mir-1976 ; hsa-mir-4279 ; hsa-mir-4722-3p ; hsa-mir-4740-3p ; hsa-mir-485-3p ; hsa-mir-539-3p ; hsa-mir-6512-5p ; hsa-mir-6727-3p ; hsa-mir-6747-3p ; hsa-mir-6778-3p
Nearest miRNA
hsa-mir-3976/Upstream/506588; hsa-mir-1-2/Downstream/1298418;
Nearest TSS
ENST00000575820/Upstream/58823; ENST00000592203/Downstream/39250;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/67686, chr18-CpG: 90/Downstream/92619
Upstream sequence
atatttgttgagtacatgacatattttggtacaggcgtgcaatgcataatagcatggagaatggggtatccatcttctcaagcattcatcttttgtgtta
Downstream sequence
caaaccatccaattatagtcttacagtccttttaaaatgtacagttattatggactatagtcaccctgttgtgctaccaaacactaggtcttattcatgc
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate