Basic Information
VIS ID
TVIS44028784
Fusion event
HTLV-1-ATP8A2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr13
Cytoband
q12.13
Reference genome
NCBI36/hg18
Start
25311325/25839187 (Hg38)
End
25311325/25839187 (Hg38)
Orient
+
Location type
Intronic
Target gene
ATP8A2
miRNAs that regulate target gene
hsa-mir-30a-5p ; hsa-mir-16-5p ; hsa-mir-675-5p ; hsa-mir-1271-5p ; hsa-mir-182-5p ; hsa-mir-196a-3p ; hsa-mir-2278 ; hsa-mir-29b-1-5p ; hsa-mir-3919 ; hsa-mir-3925-5p ; hsa-mir-4468 ; hsa-mir-5087 ; hsa-mir-6501-3p ; hsa-mir-96-5p ; hsa-mir-129-5p
Nearest miRNA
hsa-mir-2276/Upstream/1676683; hsa-mir-1267/Downstream/13824847;
Nearest TSS
ENST00000623511/Upstream/272054; ENST00000621997/Downstream/211844;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/369839, chr13-CpG: 49/Downstream/172962
Upstream sequence
GGAATGTTTTCAGTGCTTTTAAGACATCCCATCTGCCCCGACACAGTTTAATTGTTAAGAAGAGACACAGTTTTAGTCTCTTCTTAACAATTTTGACCTA
Downstream sequence
GTACCCTTTTTCTGGATGTTTGTAAAATGGTGTTGTCTCTCTTACAATGCTAAAGAAAACTGATCAGAGTGAATTTTTCACATGTGGATAGATTGTGTTG
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate