Basic Information
VIS ID
TVIS44028806
Fusion event
HTLV-1-ASCC1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr10
Cytoband
q22.1
Reference genome
NCBI36/hg18
Start
73538953/72109189 (Hg38)
End
73538953/72109189 (Hg38)
Orient
-
Location type
Intronic
Target gene
ASCC1
miRNAs that regulate target gene
hsa-mir-1287-3p ; hsa-mir-4524b-5p ; hsa-mir-4524a-5p ; hsa-mir-335-5p ; hsa-mir-646 ; hsa-mir-503-5p ; hsa-mir-6838-5p ; hsa-mir-497-5p ; hsa-mir-424-5p ; hsa-mir-195-5p ; hsa-mir-16-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p ; hsa-mir-451b ; hsa-mir-543 ; hsa-mir-3941 ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-944 ; hsa-mir-8054 ; hsa-mir-548k ; hsa-mir-548av-5p ; hsa-mir-548n ; hsa-mir-6840-3p ; hsa-mir-500b-3p ; hsa-mir-224-5p ; hsa-mir-6776-3p
Nearest miRNA
hsa-mir-1265/Upstream/318389; hsa-mir-107/Downstream/611840;
Nearest TSS
ENST00000439456/Upstream/20157; ENST00000478193/Downstream/25274;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/20714, chr10-CpG: 44/Downstream/106724
Upstream sequence
CAATAATATTATAGTAGCTAATAATAGCCAATAAAAGAGAGGACATAATGCCCTTCCAGAAGGCCTGGGGCACCTCAGATCCAAGGAGAAAGGTCAAGGG
Downstream sequence
CAGTCTGTGGGAGGAGCAATTCTTATCAACATCGTGGCCTCTATTAGGAGAGCAGCAAAAAGGCTGTTAAGTCAGTAGAACAGCTGTGATTTTTCAACCC
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate