Basic Information
VIS ID
TVIS44028829
Fusion event
HTLV-1-TXNDC12 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr1
Cytoband
p32.3
Reference genome
NCBI36/hg18
Start
52292040/52053780 (Hg38)
End
52292040/52053780 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1B
Target gene
TXNDC12
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-544a ; hsa-mir-3161 ; hsa-mir-3682-5p ; hsa-mir-2276-3p ; hsa-mir-4772-3p ; hsa-mir-138-1-3p ; hsa-mir-580-5p
Nearest miRNA
hsa-mir-12136/Upstream/217378; hsa-mir-101-1/Downstream/2000299;
Nearest TSS
ENST00000473358/Upstream/2862; ENST00000524414/Downstream/1396;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/19947, chr1-CpG: 33/Downstream/1294
Upstream sequence
acaacaaaaaaaaacGGTAGTCTGTTTTAAAATGGGATTGTCAGTATTTAAAACATTCTGGCCTAACAGGATTTGTCATGCAGTTTCATCACTGAGATGG
Downstream sequence
AAAcccacatatcaccttctccaaaaagcttctcctgaccttcataattcaagtgatgccagctccaccaacctccccagcctttctacttcctattcca
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate