Basic Information
VIS ID
TVIS44028830
Fusion event
HTLV-1-SIPA1L3 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr19
Cytoband
q13.13
Reference genome
NCBI36/hg18
Start
43104041/37921561 (Hg38)
End
43104041/37921561 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA19A
Target gene
SIPA1L3
miRNAs that regulate target gene
hsa-mir-375 ; hsa-mir-615-3p ; hsa-mir-149-5p ; hsa-mir-106a-5p ; hsa-mir-17-5p ; hsa-mir-210-3p ; hsa-mir-190a-3p ; hsa-mir-5011-5p ; hsa-mir-1277-5p ; hsa-mir-4652-3p ; hsa-mir-4743-3p
Nearest miRNA
hsa-mir-10395/Upstream/2575934; hsa-let-7e/Downstream/1488062;
Nearest TSS
ENST00000633603/Upstream/14316; ENST00000476317/Downstream/10785;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/14036, chr19-CpG: 107/Downstream/160447
Upstream sequence
AGCTCTTTCCTCTGGTGCCCCGTTTTTCTATGCTGTGCTGTTGGTTTGCAGGGAGGAAGACAGGGAAGTCCTGCACCCCCTCAAGCTTCCATAAACTTCC
Downstream sequence
ACCCCCAGCACCATCTTCATCTCTGTCCtttctttttctttctttttttttttttttgagacaaggtcttgctctttcacccagcctggagtgcagtggc
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate