Basic Information
VIS ID
TVIS44028847
Fusion event
HTLV-1-FRMD3 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr9
Cytoband
q21.32
Reference genome
NCBI36/hg18
Start
85297829/83493094 (Hg38)
End
85297829/83493094 (Hg38)
Orient
-
Location type
Intronic
Target gene
FRMD3
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-377-3p ; hsa-mir-8064 ; hsa-mir-7110-3p ; hsa-mir-8485 ; hsa-mir-342-3p ; hsa-mir-6873-3p ; hsa-mir-6817-3p ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-5007-3p ; hsa-mir-1279 ; hsa-mir-3613-3p
Nearest miRNA
hsa-mir-101-2/Upstream/12683010; hsa-let-7a-1/Downstream/476654;
Nearest TSS
ENST00000422679/Upstream/25352; ENST00000530832/Downstream/45344;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/429688, chr9-CpG: 145/Downstream/44344
Upstream sequence
TTGCAGATGCCTCCAGCTTTACAAATGATCCTTCTAGAATCCCTCCCTTGACTTTGGGGAGGAGAAGCACCCACTGCCTCTCCCTGTGTCTGTGAACACT
Downstream sequence
CCCCTCCCCAAAAAGCCGCTGACCTCACACACAAAACCCACACACATACCTTCTTTCCATCATCTCCTTACAGTCCCAGGAGTTGGAAGGGAGGAGGGAG
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate