Basic Information
VIS ID
TVIS44028850
Fusion event
HTLV-1-PGM5 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr9
Cytoband
q21.11
Reference genome
NCBI36/hg18
Start
70256214/68451478 (Hg38)
End
70256214/68451478 (Hg38)
Orient
+
Location type
Intronic
Target gene
PGM5
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-124-3p
Nearest miRNA
hsa-mir-101-2/Upstream/27217643; hsa-let-7a-1/Downstream/2358497;
Nearest TSS
ENST00000422679/Upstream/44978; ENST00000472639/Downstream/13043;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/93790, chr9-CpG: 122/Downstream/253304
Upstream sequence
TCCAGAGTGTGCGTGAGCAATATCATTGCCAATAGTTAATTAAATGAGTGACTTGTAGCCTCGTCATTTCAAAAGCAAAATTATAAAAATTCTTTCAAGT
Downstream sequence
TCTTTTGGAGCAAAAGTAGATTTTTATGTGAGATGTGGACATATTTTAATATTTTTGGTATGATATGGGATGGGGCCTCATAAACACACATTCAGAGAGT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
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