Basic Information
VIS ID
TVIS44028870
Fusion event
HTLV-1-ANK2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr4
Cytoband
q25
Reference genome
NCBI36/hg18
Start
113980697/112840092 (Hg38)
End
113980697/112840092 (Hg38)
Orient
+
Location type
Intronic
Target gene
ANK2
miRNAs that regulate target gene
hsa-mir-122-5p ; hsa-mir-335-5p ; hsa-mir-877-3p ; hsa-mir-647
Nearest miRNA
hsa-mir-12113/Upstream/191535; hsa-mir-1243/Downstream/266771;
Nearest TSS
ENST00000502981/Upstream/21983; ENST00000514246/Downstream/42238;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/133741, chr4-CpG: 86/Downstream/920821
Upstream sequence
TAATAATTGTGattcatttgataataatttattaagcaattactatatgctaggtcttgtgctatgtgctggaggtacaaagatgtataggacatggtcc
Downstream sequence
tggtccttgtcctTCCTCTAACAGCAGGCTTTAGATCAAACATCTCTGCTTGAATTAACAGGGTTTCCCAGTGTGGTTTGTAGATCAACTGCATATTCAG
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate