Basic Information
VIS ID
TVIS44028904
Fusion event
HTLV-1-GRID1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr10
Cytoband
q23.1
Reference genome
NCBI36/hg18
Start
87547144/85797407 (Hg38)
End
87547144/85797407 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA10D
Target gene
GRID1
miRNAs that regulate target gene
hsa-mir-5011-5p ; hsa-mir-190a-3p ; hsa-mir-410-3p ; hsa-mir-1277-5p ; hsa-mir-6848-3p ; hsa-mir-6843-3p ; hsa-mir-6873-3p ; hsa-mir-377-3p ; hsa-mir-6895-3p ; hsa-mir-138-5p ; hsa-mir-6131 ; hsa-mir-133a-5p ; hsa-mir-3663-5p ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-342-3p ; hsa-mir-6722-5p ; hsa-mir-6768-5p ; hsa-mir-8485 ; hsa-mir-4709-3p ; hsa-mir-4699-5p ; hsa-mir-1238-3p ; hsa-mir-670-3p ; hsa-mir-6867-3p ; hsa-mir-6749-3p ; hsa-mir-6792-3p ; hsa-mir-4691-5p ; hsa-mir-642a-5p ; hsa-mir-6826-3p ; hsa-mir-3124-3p ; hsa-mir-4287 ; hsa-mir-4685-3p ; hsa-mir-7113-3p ; hsa-mir-4469 ; hsa-mir-6769b-3p ; hsa-mir-4723-3p ; hsa-mir-3183 ; hsa-mir-660-3p ; hsa-mir-5193 ; hsa-mir-2276-5p ; hsa-mir-6892-3p ; hsa-mir-5196-3p ; hsa-mir-4283 ; hsa-mir-4448 ; hsa-mir-423-5p ; hsa-mir-3184-5p ; hsa-mir-4530 ; hsa-mir-922 ; hsa-mir-1298-3p ; hsa-mir-3126-3p ; hsa-mir-6813-5p ; hsa-mir-6856-5p ; hsa-mir-6085 ; hsa-mir-6758-5p
Nearest miRNA
hsa-mir-1265/Upstream/10244854; hsa-mir-107/Downstream/467287;
Nearest TSS
ENST00000439456/Upstream/153334; ENST00000428940/Downstream/569071;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/1256210, chr10-CpG: 47/Downstream/465476
Upstream sequence
actcgggtactgagtatagtacacaattgttggtttttcaattcacatcctcttcaccacctaccaactctagtagtccacagtgtctattatttatttc
Downstream sequence
tgtacttatttttattttattttatttatttacttttttgagaccaagttttgctcttattgcccaggctggagtgcaatggtgcaatctcagctcactg
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate