Basic Information
VIS ID
TVIS44028911
Fusion event
HTLV-1-PCDH15 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr10
Cytoband
q21.1
Reference genome
NCBI36/hg18
Start
55688429/54258663 (Hg38)
End
55688429/54258663 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA10C
Target gene
PCDH15
Nearest miRNA
hsa-mir-1265/Upstream/2959008; hsa-mir-107/Downstream/349211;
Nearest TSS
ENST00000439456/Upstream/62817; ENST00000422842/Downstream/227567;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/1386997, chr10-CpG: 36/Downstream/1369645
Upstream sequence
AAGTTAAGACCTGAGCTCTCCATATAAAACAAACCTTGTGTAACAAGTGAACCACCCAGGTATGTCTTTAAATTTATTTTTGAAACATTAGTTTCTGTCC
Downstream sequence
ttaattattttctaataaaaataaaatcatttgataaaagaaatacaataataatatCCAACGTGAATAAAGTCTGAAGACTCAGAGGGAAAATATTTTT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate